Sfoglia Chimica per Soggetto "BIO/10 BIOCHIMICA"
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A computational approach to investigate the interactions between potential pharmacological chaperones and GALT enzyme
(Universita degli studi di Salerno, 2023-03-13)Classic galactosemia is an inborn error of metabolism associated with mutations that impair the activity and the stability of the dimeric enzyme galactose-1-phosphate uridylyltransferase (GALT), which catalyzes the ... -
Molecular bases of gluten toxicity and Relationship with the enzyme Transglutaminase in celiac disease
(Universita degli studi di Salerno, 2022-06-17)Celiac disease (CD) is a life-long gluten-sensitive immune-mediated disorder that primarily affects the small intestine of genetically susceptible individuals worldwide. Type 2 transglutaminase (TG2) has two crucial roles ... -
The protein related to Pseudoxanthoma Elasticum regulates the purinergic system. New insight on the ABCC6 transporter
(Universita degli studi di Salerno, 2019-02-04)ABC (ATP-binding cassette)transporters are the largest superfamily of membrane proteins present in all organisms and they are particularity involved in transport of nutrients and drugs... [edited by Author] -
The Role of ABCC6 Transporter in the Purinergic System: from Oncology to Regenerative Medicine
(Universita degli studi di Salerno, 2022-06-20)ABCC6 is a member of ATP-binding cassette family of transporters, a class of membrane transporters sharing a common structural organization. Mutations in ABCC6 are associated with Pseudoxantoma elasticum (PXE) and with ...
